Read: Old Firm re-united
It was the 400th competitive meeting, but first since April 2012, shortly before cash-strapped Rangers was liquidated and forced to re-form as a new entity in the bottom flight of the Scottish leagues.
The 2-0 win for Celtic reflected the current status of the two clubs, one topping the Scottish Premiership, the other struggling to catch Hearts in the battle for the automatic promotion spot from the second flight.
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Fourth-placed Southampton later suffered a shock 1-0 home defeat to Swansea, ending with 10 men after Ryan Bertrand was sent off in the second half.
Jonjo Shelvey scored the Swansea goal after 83 minutes of a tight encounter.
