The girls, two of them 15 and one 16, have not been seen since Tuesday, when, police say, they took a flight to Istanbul.
One has been named as Shamima Begum, 15, who may be traveling under the name of 17-year-old Aklima Begum, and a second as Kadiza Sultana, 16. The third girl has not been named at the request of her family, police said.
Pictures released by police show the three girls walking together through London Gatwick Airport, carrying travel bags. They are said to be close friends who went to the same east London school.
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She was given a four-year prison sentence last month after admitting wanting to become an ISIS bride and participate in its jihad in the Mideast.
CNN’s Laura Perez Maestro contributed to this report.
