The 37-year-old, sacked and twice intercepted, refused to give in as the Patriotsat one point down by 10fought their way to a 28-24 victory over the Seattle Seahawks in Glendale, Arizona.
They were helped by one of the less likely calls in football history, as Seattle threw a second consecutive Super Bowl title into the hands of Malcolm Butler.
Patriots rookie Butler made a game-saving interception when the Seahawks, with the ball on the one-yard line and seconds to play, mysteriously chose to pass after an improbable, juggling miracle-catch by Jermaine Kearse.
That moment gave Brady and coach Bill Belichick a fourth Super Bowl victory, a feat matched by only two other quarterbacks: Joe Montana and Terry Bradshaw.
“I just had a vision that I was going to make a big play and it came true,” said Butler, 24.
MVP Brady said: “This has been a long journey. I’ve been at it for 15 years. This one came down to the end and this time, we made the plays.
Following that staggering climax, the game’s dying moments descended into a mass brawl which led to the ejection of the Seahawks’ Bruce Irvin.
By that point, the fight simply delayed an inevitable New England victory.
“I can’t even tell you, I can’t even feel it,” said Seahawks coach Pete Carroll of the decision to throw the ball.
“For it to come down to a play like that, I hate that we have to live with that.”
New England’s Edelman said: “We made more plays, we executed when we had to, we have a mentally tough team that works their tails off.
“We are the epitome of what Boston is all about.”