Why Some Vaccines Require More Than One Dose

Despite being declared beaten in 2000, measles is back, due largely to declining vaccination rates in parts of the United States.

“We should not be in this boat,” Dr. Pritish Tosh, an infectious diseases physician and researcher at the Mayo Clinic, told The Huffington Post. “This is a completely preventable disease.”

That doesn’t mean that a child who has had only a single dose of, say, the measles vaccine, is unprotected. “Some people may on one dose generate [a] long-lasting and very specific immune response. Some people may need two doses,” said Tosh. “It’s difficult to determine who those people are going to be.” Which is why, he stressed, “I would recommend if people have not gotten their full initial complement of vaccines, to get their catchup doses.”

The Huffington Post